- The Cardinals purchased Bob Grim from the Cincinnati Reds in 1960.
- The New York Mets, in 1963, traded Jacke Davis and cash to the Cardinals for Duke Carmel.
- The St. Louis Cardinals traded Jose Cardenal, Bob Reynolds and Dick Schofield to the Milwaukee Brewers in 1971, for Chuck Loseth (minors) and Ted Kubiak
- In 2000, the Baltimore Orioles traded Mike Timlin and cash to the St. Louis Cardinals for Mark Nussbeck (minors) and Chris Richard.
- The Pirates traded Jason Christiansen to the St. Louis Cardinals for Jack Wilson in 2000.
- The Phillies in 2002 traded Doug Nickle, Scott Rolen and cash to the St. Louis Cardinals for Placido Polanco, Bud Smith and Mike Timlin.
- Yankees traded Giovanny Gallegos and Chasen Shreve to the St. Louis Cardinals for Luke Voit and international bonus slot money in 2018.
- Emmet Heidrick 1876
- Fred Smith 1891
- Francis Healy 1910
- Erv Dusak 1920
- Dan Driessen 1951
- Dave LaPoint 1959
- Luis Alicea 1965
- Mark Hamilton 1980
- Jesse Fowler 1924
- Tommy Thevenow 1957
- Bart Shotton 1962