Marty Marion is named NL MVP and also Player of the Year by the Sporting News in 1944. He was the first Cardinals player to receive this honor.
- After Pirates manager Danny Murtaugh rejects the A’s offer in 1959 to deal Roger Maris for shortstop Dick Groat, Pittsburgh obtains Gino Cimoli along with Tom Cheney from the Cardinals for right-hander Ron Kline.
- The Cardinals purchased Danny Breeden from the Chicago Cubs in 1964.
- The Cardinals purchased Rick Honeycutt in 1995 from the New York Yankees.
- Alan Benes was granted free agency in 2001.
- So Taguchi in 2004 was granted free agency.
- In 2005, Bo Hart, Sidney Ponson, and John Riedling were granted free agency.
- Cardinals signed Jeremy Hefner as a free agent in 2015.
- Hal Heid (1897)
- Bill Werle (1920)
- Joaquin Andujar (1952)
- Tom Henke (1957)
- Andy Van Slyke (1960)
- Dustin Hermanson 1962
- Ed Easley (1985)
- Cody Stanley (1988)
- Jack Warner 1943
- Tony Jacobs 1980
- Jack Lamabe 2007
- Bud Bloomfield 2011