Trades and Transactions
- The Boston Braves drafted Ira Hutchinson from the Cardinals in the 1943 rule 5 draft.
- The New York Giants drafted Slim Emmerich from the Cardinals in the 1944 rule 5 draft.
- The Boston Braves drafted Danny Murtaugh from the Cardinals in the 1946 rule 5 draft.
- Jose Oquendo and Tom Henke were granted free agency in 1995.
- In 2002, Mike Difelice was granted free agency.
- Jamey Wright was granted free agency in 2002.
- In 2004, Steve Kline, Tony Womack and Matt Morris were granted free agency.
- In 2006, Jeff Weaver was granted free agency.
- Jason Isringhausen was granted free agency in 2008
- Jake Westbrook, in 2013, was granted free agency.
- 2022- Albert Pujols files for retirement.
- 2022- Yadier Molina file for retirement.
- 2022 Nolan Arenado wins his 10th consecutive Gold Glove.
- 2022 Rookie Brendan Donovan wins his first gold glove as a utility player.
- Ernie Lush 1885 – played his one and only game on July 20,1910. He had 4 at bats and no hits. He played in the outfield.
- Heinie Schuble 1906 – infielder that played professional baseball for 11 years from 1926 to 1936, including seven seasons in Major League Baseball with the St. Louis Cardinals (1927 and 1936) and Detroit Tigers (1929–1935). He appeared in 332 major league games (172 at shortstop, 106 at third base) and compiled a .251 batting average and .296 on-base percentage. MLB debut July 8, 1927, for the St. Louis Cardinals
Last MLB appearance May 15, 1936, for the St. Louis Cardinals
- Jim Kennedy 1946 an infielder appeared in 12 games in Major League Baseball for the 1970 St. Louis Cardinals as a shortstop (seven games) and as a second baseman (five games). Debut on June 14,1970 and played last game on July 9,1970.
- Fernando Valenzuela 1960- played with success for the Dodgers and came to Cardinals late in his career. In 1997 he played for the Cardinals.
- Benny Frey 1937-He is buried in Woodland Cemetery in Jackson, Michigan.
- Tom Cheney 2001- buried Morgan Methodist Church Cemetery Morgan, Calhoun County, Georgia, USA
- Jim O’Rourke 2021 – buried in Walla Walla, Washington