- In 2011, Mike Matheny is named to succeed Tony La Russa, who retired as the manager of the Cardinals a few days after leading the Redbirds to a world championship. The 41-year-old former minor league instructor, who served as a special assistant to general manager John Mozeliak, has no previous managerial experience.
- John Munyan (1887)
- Gil Paulsen (1902
- Steve Peters (1962)
- Kent Bottenfield 1968
- The Cardinals, in 1985, released Bill Campbell.
- The Cardinals signed Travis Smith as a free agent in 2001.
- In 2002, the Cardinals signed Dan Serafini as a free agent.
- The Cardinals sign Rico Washington as a free agent in 2007.
- The Cardinals release Kyle McClellan in 2012.
- Jack O’Connor 1937
- Bill Sherdel 1968