- Major League Baseball mandates all baseball personnel coach bases must wear a helmet on the field. This came after former Cardinal Mike Coolbaugh was struck in the head coaching first base in a minor league game and died on the field (July 22, 2007).
- Cardinals released Mike Laga in 1988.
- The Cardinals, in 1984, granted free agency to Bruce Sutter.
- 2016 – Winners of the Gold Glove are announced in both leagues. Yadier Molina’s eight-year reign as the National League’s best defensive catcher ends, as the honor goes to Buster Posey.
Mike Knode 1895 -In 1920, he played Major League Baseball as a right fielder, second baseman and shortstop for the St. Louis Cardinals. In 42 games, he accumulated a .231 batting average and a .306 on-base percentage.
Wally Westlake 1920 -was a utility player in Major League Baseball who had a ten-year career from 1947 to 1956.On August 26, 1947, Westlake became the first white batter hit by a pitch from a black pitcher – Dan Bankhead of the Brooklyn Dodgers at Ebbets Field.
Joe Nossek 1940– In the middle of the 1969 campaign, he was traded to the St. Louis Cardinals for Bob Johnson. He only played in 10 games for St. Louis, however, and retired after the 1970 season. Overall, Nossek batted .228 with three home runs and 53 runs batted in in 295 games during his six-year major league playing career
John Denny 1952 -entered the St. Louis starting rotation. In 1976, Denny had a breakout season. He led the National League in ERA at 2.52 and was the best pitcher on the club. Due to poor run support, his record was just 11–9. Denny also pitched well in 1978, going 14–11 with a 2.96 ERA, but he fell off badly in 1979 and was traded with Jerry Mumphrey from the Cardinals to the Indians for Bobby Bonds on December 7, 1979.
Nick Punto 1977 -On January 21, 2011, Punto signed a one-year contract with the St. Louis Cardinals worth $700,000. He played in 63 games with the Cardinals as a utility player, and hit .278 with a career high .388 on-base percentage, a home run and 20 RBI in 133 at bats. Punto had three hits in 14 at-bats (.214) with five walks in the 2011 World Series as the Cardinals defeated the Texas Rangers in seven games, giving Punto his first World Series ring.
- Cupid Childs 1912
- Joe Connor 1957
- Ray Shepardson 1975
- Les Backman 1975